What is BiMix?

  • BiMix is an injectable compounded medication used to treat erectile dysfunction (ED). It contains two active ingredients: papaverine and phentolamine.
  • BiMix is typically injected into the penis using a very fine needle. The medication relaxes the smooth muscles in the penis, which allows blood to flow into the erectile tissue. This increased blood flow results in an erection.BiMix is a prescription medication that must be prescribed by a healthcare provider and mixed at a compounding pharmacy like SandsRx.
  • BiMix injections are a safe and effective treatment for ED, but they should only be used under the supervision of a healthcare provider.

Erectile Dysfunction (ED)

Erectile dysfunction (ED) is the inability to get or keep an erection firm enough for sexual intercourse. It can happen at any age but is more common in men over 40. ED can be caused by physical or psychological problems. Approximately 20 million men in the United States suffer from ED, with that number projected to increase to more than 300 million by 2025 [1].

 

The use of oral phosphodiesterase type 5 (PDE5) inhibitors such as Sildenafil and Tadalafil is a first-line treatment for men with erectile dysfunction. These work by relaxing the corpus cavernosum inside one’s penis, thus leading to penile Hardness and Erection [2].

 

Though PDE5 inhibitors are a common treatment option, many men don’t respond to these medications as they would hope and look elsewhere for ED treatment. An alternative option that has been used with positive results in ED treatment is Bimix.

Components of BiMix Injections

BiMix ED injections contain a mixture of two drugs: Phentolamine and Papaverine. This drug is a specialty compounded medication and is therefore not available at retail pharmacies. If you’re interested in trying BiMix to help treat ED, talk to your doctor and we will work with them to create a custom dosage for you.

 

The components of BiMix work synergistically causing sustained penile erections in individuals suffering from ED.

 

BiMix is an injectable ED treatment that can be compounded to fit the needs of each person. This drug has been proven effective in treating erectile dysfunction and works better for some men than oral medications such as PDE5 inhibitors like Viagra®, which are often not strong enough for many people’s conditions.

How does BiMix work?

Injecting BiMix into the corpus cavernosum results in the relaxation, expansion, and filling of the corpus cavernosum with blood. This may result in penile erections that last throughout the duration of sexual intercourse.[3]

More About BiMix for ED Treatment

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  • Why Take BiMix For ED Treatment?
  • Side Effects of BiMix
  • Who Should Not Take BiMix?
  • Storage
  • How to Self-Administer

Why Do Men Take BiMix?

There are two primary reasons that men with ED may consider using BiMix:

  1. Failed treatment with first-line therapy such as PDE5 inhibitors.
  2. Hypersensitivity or other reactions to PDE5 inhibitors.

Side Effects of BiMix

  1. Mild pain during injection process
  2. Painful sensation during erection
  3. Small amount of bleeding at the injection site.
  4. If you notice any redness, lumps or swelling in the erect penis, let your healthcare provider know immediately. The prescribing physician should be consulted for further advice on how to proceed accordingly.

Who Should Not Take BiMix For ED Treatment?

Do not take this medicine with any of the following Conditions:

  • Do not take this medicine with any of the following conditions: hypersensitivity or allergy to any component of this formulation.
  • Conditions predisposing you to priapism (painful erection lasting 4 hours or more)
  • Sickle cell anemia
  • Multiple myeloma or leukemia
  • Anatomical deformation of the penis or penile implants
  • Direction by your physician that sexual activity is inadvisable or contraindicated.

Storage

  • Keep refrigerated or frozen as directed and protect from light.
  • Kids should never have access to BiMix injections so make sure it’s out of their reach
  • Throw away any unused medications after the beyond-use date
  • Lastly, do not flush used needles down a sink or toilet

How to Self-Administer BiMix ED Injections

Some men may feel anxious or squeamish about self-injecting themselves, this is a relatively painless procedure if done properly with the correct technique. Discussed below are the steps that are needed to safely self-administer the BiMix injection [5][6]

  • Wash your hands thoroughly with soap and water or an alcohol-based solution
  • Wipe the top of the rubber stopper thoroughly with an alcohol pad.
  • Insert a syringe into the vial through the rubber stopper and draw out the prescribed amount of BiMix into the syringe. Ensure that there are no air bubbles by tapping the syringe.
  • Find an injection site on the penis. Do not inject at the top or the bottom of the penis. Also avoid injecting directly into any visible veins or arteries on the penis, as well as along the midline. The optimal locations to administer the BiMix ED injection are at the sides of the penis. Avoid using the same spot repeatedly for injections as this may result in the scarring of penile tissue.
  • Thoroughly wipe injection site with a fresh alcohol swab.
  • Insert the needle into the penis and slowly depress the plunger to release the BiMix ED medication into the corpora cavernosa of the penis. Remove and carefully dispose of the syringe when this completed.
  • Apply pressure to the injection site and massage the penis to ensure thorough distribution of the medication throughout the tissues inside the penis.

 

The effects of BiMix become evident about 5 – 15 minutes after its injection into the penis as it induces a penile erection. Its duration action typically varies depending on the individual, ranging anywhere between half an hour to an hour. However, its effects should not last longer than 3 hours. If it does, call your physician.

SandsRx Compounding Pharmacy Offers BiMix For ED Treatment Near Dallas, TX

 

SandsRx Pharmacy specializes in urology compounding and men’s health and we are pleased to offer BiMix injections for ED treatment for patients in Dallas-Ft Worth, all of Texas, and throughout the United States. BiMix is a safe and effective medication that can be self-administered by patients in the privacy of their own homes, or by a doctor. If you are interested in BiMix injections for the treatment of ED, please contact SandsRx today to schedule an appointment. We have three pharmacy locations in Wylie, Frisco, and McKinney, TX and we are very proud to be a trusted compounding pharmacy serving the entire Dallas and Fort Worth area. If you are out of state, we can offer personalized, compassionate care for you too, as we ship to all 50 states.

References

 

Montague DK, Jarow JP, Broderick GA, et al. Chapter 1: The management of erectile dysfunction: an AUA update. J Urol 2005;174:230-9.

Leungwattanakij S, Flynn V, Hellstrom WJG. Intracavernosal injection and intraurethral therapy for erectile dysfunction. Urol Clin North Am 2001;28:343-354.

Delcour, C., et al., The effect of papaverine on arterial and venous hemodynamics of erection. J Urol, 1987. 138(1): p. 187-9.

Mooradian, A.D., et al., Biweekly intracavernous administration of papaverine for erectile dysfunction. West J Med, 1989. 151(5): p. 515-7.

Dinsmore, W.W., Medical treatment of impotence with papaverine and phentolamine intracavernosal injection. Ulster Med J, 1990. 59(2): p. 174-6.

Keogh, E.J., et al., Treatment of impotence by intrapenile injections of papaverine and phenoxybenzamine: a double blind, controlled trial. Aust N Z J Med, 1989. 19(2): p. 108-12.

Kirkeby, H.J., et al., [Infusion cavernosography and erectile dysfunction]. Ugeskr Laeger, 1990. 152(24): p. 1724-6.