General Information
Testosterone cypionate is a slow-acting, long-ester, oil-based injectable testosterone compound that is commonly prescribed for the treatment of low testosterone levels and various related symptoms in males.
Indications and uses
Testosterone Injection is indicated for replacement therapy in the male in conditions associated with symptoms of deficiency or absence of endogenous testosterone.
Contraindications
- Known hypersensitivity to the drug
- Males with carcinoma of the breast
- Males with known or suspected carcinoma of the prostate gland
- Women who are or who may become pregnant
- Patients with serious cardiac, hepatic, or renal disease
Warnings and Precautions
Pregnancy
Testosterone is contraindicated during pregnancy because of probable adverse effects on the fetus (FDA pregnancy risk category X).
Women of childbearing potential who are receiving testosterone treatments should utilize adequate contraception.
Adverse Reactions
The following adverse reactions in the male have occurred with some androgens:
Testosterone injection may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
- Acne
- Breast enlargement or pain
- Hoarseness
- Deepening of voice
- Pain, redness, bruising, bleeding, or hardness at injection site
- Tiredness
- Difficulty falling asleep or staying asleep.
- Mood swings
- Weight gain
- Headache
- Joint pain
- Back pain
- Lower leg pain, swelling, warmth, or redness.
- Nausea or vomiting
- Swelling of the hands, feet, ankles, or lower legs
- Difficulty breathing, especially during sleep.
- Erections that happen too often or that last too long.
- Difficulty urinating, weak urine flow, frequent urination, sudden need to urinate right away, blood in the urine.
- Yellowing of the skin or eyes
- Pain in the upper right part of the stomach
- Mood changes including depression, anxiety, or becoming suicidal (thinking about harming or killing oneself or planning or trying to do so)
Drug Abuse and Dependence
Testosterone is a controlled substance under the Anabolic Steroids Control Act, and DEPO-Testosterone Injection has been assigned to Schedule III.
Overdosage
There have been no reports of acute overdosage with the androgens.
Dosage and Administration
It should not be given intravenously. Intramuscular injections should be given deep in the gluteal muscle.
